BCL2 gene break apart rearrangement probe, BCL2 (CE-IVD)

Catalog No : FP-037
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Product name BCL2 gene break apart rearrangement probe, BCL2 (CE-IVD)
Catalog No FP-037
Supplier’s Catalog No FP-037
Supplier Wuhan Healthcare Biotech
Source antigen BCL2
Reactivity BCL2
Cross reactivity None
Applications Fluorescence In Situ Hybridization (FISH)
Molecular weight N/A
Storage -20°C
Other names
Grade Molecular diagnostic grade
Purity N/A
Form Liquid
Reactivity life 12 months when stored properly according to instructions
Note For Professional In Vitro diagnostics
Description Follicular lymphoma (FL) is a less malignant B cell tumor derived from the center of follicle development. FL is a common type of non-Hodgkin's lymphoma (NHL), accounting for about 10% of NHL in China and 25%-45% of NHL in Europe and America. BCL2/IGH rearrangement occurs in approximately 80%-85% of FL, t(14;18) (q32;q21) reciprocal translocation of BCL2 proto-oncogene with ICH gene; BCL2/IGH rearrangement survival rate is shortened, prognosis difference. In addition to its primary fusion with the IGH gene, it has also been found that BCL2 can be fused to other genes (eg AFF3, IGHL, etc.).