Recombinant Human Ephrin-A4 (EFNA4), partial Active

Catalog No : IGX-RP2027-1MG
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Product name Recombinant Human Ephrin-A4 (EFNA4), partial Active
Catalog No IGX-RP2027-1MG
Supplier’s Catalog No IGX-RP2027-1MG
Supplier ImuGeX
Source antigen Recombinant, expressed in E.Coli, 26-171 Amino Acids
Reactivity Rhesus macaque
Cross reactivity Rhesus macaque
Applications Functional studies, Bioassays or User optimised
Molecular weight 14.0 KDa
Storage Store at -20℃/-80℃.
Other names Ephrin-A4; EPH-Related Receptor Tyrosine Kinase Ligand 4; LERK-4; EFNA4; EPLG4; LERK4
Grade Highly Purified
Purity >98% determined by SDS-PAGE and HPLC, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Form Lyophilized from a 0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.2
Reactivity life 12 months, when stored accoring to instructions.
Note For reserch purpose only, not for In Vivo use or as therapeutics.
Purity >98% determined by SDS-PAGE and HPLC, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Description Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils. Sequence: LRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEGPRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERKSESAHPVGSPGESG. Biological Activity: The ED50 as determined by its ability to bind Human EphA7 in functional ELISA is less than 10 ug/ml.