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Categories: Peptides & Proteins / Proteins

Product name			Recombinant Human Leptin protein (LEP) Active
Catalog No			IGX-RP2028-5MG
Supplier’s Catalog No			IGX-RP2028-5MG
Supplier			ImuGeX
Source antigen			Recombinant, expressed in E.Coli, 22-167 Amino Acids
Reactivity			Rhesus macaque
Cross reactivity			Rhesus macaque
Applications			Functional studies, Bioassays or User optimised
Molecular weight			14.9 KDa

Storage			Store at -20℃/-80℃.
Other names			Obese protein,
Grade			Highly Purified
Purity			>96% determined by SDS-PAGE and HPLC, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Form			Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reactivity life			12 months, when stored accoring to instructions.
Note			For reserch purpose only, not for In Vivo use or as therapeutics.
Purity			>96% determined by SDS-PAGE and HPLC, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Description			Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways Sequence: VPIQKVQDDT KTLIKTIVTR INDISHTQSV SSKQKVTGLD FIPGLHPILT LSKMDQTLAV YQQILTSMPS RNVIQISNDL ENLRDLLHVL AFSKSCHLPW ASGLETLDSL GGVLEASGYS TEVVALSRLQ GSLQDMLWQL DLSPGC. Biological Activity: Biologically Fully Active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human Leptin R transfected BaF3 murine proB cells is less than 2 ng/ml, corresponding to a specific activity of ＞ 5.0 × 105 IU/mg.