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Categories: Peptides & Proteins / Proteins

Product name			Recombinant Human Tumor necrosis factor receptor superfamily member 11A protein (TNFRSF11A) Active
Catalog No			IGX-RP2046-1MG
Supplier’s Catalog No			IGX-RP2046-1MG
Supplier			ImuGeX
Source antigen			Recombinant, expressed in E.Coli, 29-202 Amino Acids
Reactivity			Mouse
Cross reactivity			Mouse
Applications			Functional studies, Bioassays or User optimised
Molecular weight			14.8 KDa

Storage			Store at -20℃/-80℃.
Other names			Osteoclast differentiation factor receptor, Receptor activator of NF-KB, CD antigen CD265
Grade			Highly Purified
Purity			>98% determined by SDS-PAGE and HPLC, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Form			Lyophilized from a 0.2 µm filtered 20 mM Tris-HCl, pH 8.0, 150mM NaCl
Reactivity life			12 months, when stored accoring to instructions.
Note			For reserch purpose only, not for In Vivo use or as therapeutics.
Purity			>98% determined by SDS-PAGE and HPLC, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Description			Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. Sequence: QIAPPCTSEK HYEHLGRCCN KCEPGKYMSS KCTTTSDSVC LPCGPDEYLD SWNEEDKCLL HKVCDTGKAL VAVVAGNSTT PRRCACTAGY HWSQDCECCR RNTECAPGLG AQHPLQLNKD TVCKPCLAGY FSDAFSSTDK CRPWTNCTFL GKRVEHHGTE KSDAVCSSSL PARK56. Biological Activity: Biologically Fully Active when compared to standard. The ED50 as determined by its ability to inhibit sRANK Ligand induced nuclear factor kappa B (NF-kappa B) in RAW 264.7 cells is less than 50 ng/ml, corresponding to a specific activity of ＞ 2.0 × 104 IU/mg in the presence of 15 ng/ml of recombinant sRANK Ligand.