Recombinant Human herpesvirus 8 type P protein (VMI2) Active

Catalog No : IGX-RP2120-1MG
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Product name Recombinant Human herpesvirus 8 type P protein (VMI2) Active
Catalog No IGX-RP2120-1MG
Supplier’s Catalog No IGX-RP2120-1MG
Supplier ImuGeX
Source antigen Recombinant, expressed in E.Coli, 24-93 Amino Acids
Reactivity Human
Cross reactivity Human
Applications Functional studies, Bioassays or User optimised
Molecular weight 8.4 KDa
Storage Store at -20℃/-80℃.
Other names Viral macrophage inflammatory protein II Short name:vMIP-II vMIP-1B
Grade Highly Purified
Purity >97% determined by SDS-PAGE and HPLC, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Form Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reactivity life 12 months, when stored accoring to instructions.
Note For reserch purpose only, not for In Vivo use or as therapeutics.
Purity >97% determined by SDS-PAGE and HPLC, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Description Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions. Sequence: LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA140. Biological Activity: Biologically Fully Active when compared to standard. The specific activity is determined by the inhibitory effect on monocyte migration response to human MIP-1 alpha using a concentration range of 1.0µg-10.0µg/ml of viral MIP-2 will inhibit 25ng/ml of human MIP-1 alpha.