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Categories: Peptides & Proteins / Proteins

Product name			Recombinant Human Nectin-4 (NECTIN4), partial Active
Catalog No			IGX-RP2154-1MG
Supplier’s Catalog No			IGX-RP2154-1MG
Supplier			ImuGeX
Source antigen			Recombinant, expressed in E.Coli, 31-351 Amino Acids
Reactivity			Mouse
Cross reactivity			Mouse
Applications			Functional studies, Bioassays or User optimised
Molecular weight			7.8 KDa

Storage			Store at -20℃/-80℃.
Other names			PVRL4;Nectin-4;Ig superfamily receptor LNIR;Poliovirus receptor-related protein 4;PRR4;LNIR
Grade			Highly Purified
Purity			>97% determined by SDS-PAGE and HPLC, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Form			Lyophilized from a 0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.4
Reactivity life			12 months, when stored accoring to instructions.
Note			For reserch purpose only, not for In Vivo use or as therapeutics.
Purity			>97% determined by SDS-PAGE and HPLC, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Description			Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.; FUNCTION Sequence: AGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVV. Biological Activity: Specific activity as determined by the ability of the immobilized protein to support the adhesion of NIH‑3T3 mouse embryonic fibroblast cells is greater than 40%. When 5 x 10^4 cells/well are added to plates coated with recombinant human Nectin-4 (1 µg/mL with 100 µL/well), approximately >68.8% will adhere after 40 min incubation at 37 °C.