Recombinant Mouse C-C motif chemokine 5 protein (Ccl5) Active

Catalog No : IGX-RP2361-250UG
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Product name Recombinant Mouse C-C motif chemokine 5 protein (Ccl5) Active
Catalog No IGX-RP2361-250UG
Supplier’s Catalog No IGX-RP2361-250UG
Supplier ImuGeX
Source antigen Recombinant, expressed in E.coli
Reactivity Human
Cross reactivity Human
Applications Functional studies, Bioassays or User optimised
Molecular weight 22.6 KDa
Storage Store at -20℃/-80℃.
Other names MuRantes, Small-inducible cytokine A5, T-cell-specific protein RANTES
Grade Highly Purified
Purity >95% determined by SDS-PAGE, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Form Lyophilized
Reactivity life 12 months, when stored accoring to instructions.
Note For reserch purpose only, not for In Vivo use or as therapeutics.
Purity >95% determined by SDS-PAGE, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Description Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Sequence: SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS. Tag info:Tag-Free