Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (TNFSF18) Active

Catalog No : IGX-RP2590-20UG
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Product name Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (TNFSF18) Active
Catalog No IGX-RP2590-20UG
Supplier’s Catalog No IGX-RP2590-20UG
Supplier ImuGeX
Source antigen Recombinant, expressed in E.coli
Reactivity Human
Cross reactivity Human
Applications Functional studies, Bioassays or User optimised
Molecular weight 46.9 KDa
Storage Store at -20℃/-80℃.
Other names Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand, hGITRL
Grade Highly Purified
Purity >85% determined by SDS-PAGE, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Form Liquid or Lyophilized
Reactivity life 12 months, when stored accoring to instructions.
Note For reserch purpose only, not for In Vivo use or as therapeutics.
Purity >85% determined by SDS-PAGE, Endotoxin Level: <1.0 EU/µg as determined by LAL method.
Description Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 Sequence: ETAKEPCMAK FGPLPSKWQM ASSEPPCVNK VSDWKLEILQ NGLYLIYGQV APNANYNDVA PFEVRLYKNK DMIQTLTNKS KIQNVGGTYE LHVGDTIDLI FNSEHQVLKN NTYWGIILLA NPQFIS140