Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (TNFSF18) Active
Catalog No : IGX-RP2590-20UG
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Product name | Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (TNFSF18) Active | ||
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Catalog No | IGX-RP2590-20UG | ||
Supplier’s Catalog No | IGX-RP2590-20UG | ||
Supplier | ImuGeX | ||
Source antigen | Recombinant, expressed in E.coli | ||
Reactivity | Human | ||
Cross reactivity | Human | ||
Applications | Functional studies, Bioassays or User optimised | ||
Molecular weight | 46.9 KDa |
Storage | Store at -20℃/-80℃. | ||
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Other names | Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand, hGITRL | ||
Grade | Highly Purified | ||
Purity | >85% determined by SDS-PAGE, Endotoxin Level: <1.0 EU/µg as determined by LAL method. | ||
Form | Liquid or Lyophilized | ||
Reactivity life | 12 months, when stored accoring to instructions. | ||
Note | For reserch purpose only, not for In Vivo use or as therapeutics. | ||
Purity | >85% determined by SDS-PAGE, Endotoxin Level: <1.0 EU/µg as determined by LAL method. | ||
Description | Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 Sequence: ETAKEPCMAK FGPLPSKWQM ASSEPPCVNK VSDWKLEILQ NGLYLIYGQV APNANYNDVA PFEVRLYKNK DMIQTLTNKS KIQNVGGTYE LHVGDTIDLI FNSEHQVLKN NTYWGIILLA NPQFIS140 |
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