Anti-Phospho-PTEN (Ser380) Antibody
Catalog No : IGX-40101
265.00€
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| Description | Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4 | ||
|---|---|---|---|
| Other names | BZS, DEC, GLM2, MHAM, TEP1, Phospho PTEN Ser380, Phospho PTEN S380 | ||
| Cellular localization | Nucelus, Cytoplasm | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P60484 | ||
| Product name | Anti-Phospho-PTEN (Ser380) Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40101 | ||
| Supplier’s Catalog No | IGX-40101 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse, Rat | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:50-1:100, IF: 1:100-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Phosphopeptide derived from human PTEN around the phosphorylation site of serine 380 (R-Y-SP-D-T). | ||
| Specificity | Phospho-PTEN (Ser380) antibody detects endogenous level of Phospho-PTEN protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.02% sodium azide and 50% glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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