Anti-2-hydroxyisobutyryl-Histone H1C (K22) Antibody
Catalog No : IGX-40108
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation . | ||
|---|---|---|---|
| Other names | Histone H1.2, Histone H1c, Histone H1d, Histone H1s-1, HIST1H1C, H1F2 | ||
| Cellular localization | Nucleus, Chromosome | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P16403 | ||
| Product name | Anti-2-hydroxyisobutyryl-Histone H1C (K22) Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40108 | ||
| Supplier’s Catalog No | IGX-40108 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, ICC, IF | ||
| Recommended dilutions | ICC: 1:1-1:10, IF: 1:1-1:10 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Peptide sequence around site of 2-hydroxyisobutyryl-Lys (22) derived from Human Histone H1.2 | ||
| Specificity | 2-Hydroxyisobutyryl-HIST1H1C (K22) antibody detects endogenous level of 2-Hydroxyisobutyryl-HIST1H1C (K22) protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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