Anti-2-hydroxyisobutyryl-Histone H1C (K22) Antibody

Catalog No : IGX-40108
262.00€
188.00€

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Description Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation .
Other names Histone H1.2, Histone H1c, Histone H1d, Histone H1s-1, HIST1H1C, H1F2
Cellular localization Nucleus, Chromosome
Research area Epigenetics & Nuclear Signaling
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P16403
Product name Anti-2-hydroxyisobutyryl-Histone H1C (K22) Antibody
Catalog No IGX-40108
Supplier’s Catalog No IGX-40108
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, ICC, IF
Recommended dilutions ICC: 1:1-1:10, IF: 1:1-1:10
Molecular weight N/A
Conjugate Unconjugated
Immunogen Peptide sequence around site of 2-hydroxyisobutyryl-Lys (22) derived from Human Histone H1.2
Specificity 2-Hydroxyisobutyryl-HIST1H1C (K22) antibody detects endogenous level of 2-Hydroxyisobutyryl-HIST1H1C (K22) protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).