Anti-2-hydroxyisobutyryl-Histone H2A type 1 (K36) Antibody

Catalog No : IGX-40113

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Description Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Other names Histone H2A type 1, H2A.1, Histone H2A/ptl, HIST1H2AG, HIST1H2AI, HIST1H2AK, HIST1H2AL, HIST1H2AM, H2AFP, H2AFC, H2AFD, H2AFI, H2AFN
Cellular localization Nucleus, Chromosome
Research area Epigenetics & Nuclear Signaling
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P0C0S8
Product name Anti-2-hydroxyisobutyryl-Histone H2A type 1 (K36) Antibody
Catalog No IGX-40113
Supplier’s Catalog No IGX-40113
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, ICC
Recommended dilutions ICC: 1:10-1:100
Molecular weight N/A
Conjugate Unconjugated
Immunogen Peptide sequence around site of 2-hydroxyisobutyryl-Lys (36) derived from Human Histone H2A type 1
Specificity 2-Hydroxyisobutyryl-HIST1H2AG (K36) antibody detects endogenous level of 2-Hydroxyisobutyryl-HIST1H2AG (K36) protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).