Anti-KIR3DL2 Antibody

Catalog No : IGX-40218
262.00€
188.00€

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Description Receptor on natural killer (NK) cells and T cells for MHC class I molecules (PMID:24018270, PMID:28636952). Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions (PMID:24018270). Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity (PMID:26928464).
Other names Killer cell immunoglobulin-like receptor 3DL2, CD158 antigen-like family member K, MHC class I NK cell receptor, Natural killer-associated transcript 4, NKAT-4, p70 natural killer cell receptor clone CL-5, p70 NK receptor CL-5, CD antigen CD158k, KIR3DL2, CD158K NKAT4
Cellular localization Membrane
Research area Immunology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P43630
Product name Anti-KIR3DL2 Antibody
Catalog No IGX-40218
Supplier’s Catalog No IGX-40218
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IF
Recommended dilutions IF: 1:200-1:500
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Killer cell immunoglobulin-like receptor 3DL2 protein (361-455AA)
Specificity KIR3DL2 antibody detects endogenous level of KIR3DL2 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).