Anti-Lypla1 Antibody
Catalog No : IGX-40238
262.00€
188.00€
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| Description | Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS . Has depalmitoylating activity toward KCNMA1 . Acts as a lysophospholipase hydrolyzing various lysophospholipids including lysophosphatidylcholine (lyso-PC), lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS)(PMID:9139730). Has much higher thioesterase activity than lysophospholipase activity . Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA . | ||
|---|---|---|---|
| Other names | Acyl-protein thioesterase 1, APT-1, EC 3.1.2.-, Lysophospholipase 1, Lysophospholipase I, LPL-I, LysoPLA I, Lypla1, Apt1 Pla1a | ||
| Cellular localization | Membrane, Cytoplasm, Endoplasmic Reticulum, Membrane, Nucleus | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P97823 | ||
| Product name | Anti-Lypla1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40238 | ||
| Supplier’s Catalog No | IGX-40238 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Mouse | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Mouse Acyl-protein thioesterase 1 protein (1-230AA) | ||
| Specificity | Lypla1 antibody detects endogenous level of Lypla1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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