Anti-TMEM106A Antibody
Catalog No : IGX-40249
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway. Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide . May play a role in inhibition of proliferation and migration (PMID:30456879, PMID:29131025). | ||
|---|---|---|---|
| Other names | Transmembrane protein 106A, TMEM106A | ||
| Cellular localization | Membrane, Single-Pass Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q96A25 | ||
| Product name | Anti-TMEM106A Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40249 | ||
| Supplier’s Catalog No | IGX-40249 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Transmembrane protein 106A protein (1-94AA) | ||
| Specificity | TMEM106A antibody detects endogenous level of TMEM106A protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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