Anti-LYPLA2 Antibody
Catalog No : IGX-40257
262.00€
188.00€
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| Description | Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS (PMID:21152083, PMID:28826475). Deacylates GAP43 (PMID:21152083). Mediates depalmitoylation of ZDHHC6 (PMID:28826475). Has lysophospholipase activity (PMID:25301951). Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G) (PMID:25301951). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide (PMID:25301951). | ||
|---|---|---|---|
| Other names | Acyl-protein thioesterase 2, APT-2, EC 3.1.2.-, Lysophospholipase II, LPL-II, LysoPLA II, LYPLA2, APT2 | ||
| Cellular localization | Cytoplasm | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O95372 | ||
| Product name | Anti-LYPLA2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40257 | ||
| Supplier’s Catalog No | IGX-40257 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Acyl-protein thioesterase 2 protein (1-226AA) | ||
| Specificity | LYPLA2 antibody detects endogenous level of LYPLA2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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