Anti-TSHR Antibody

Catalog No : IGX-40261
262.00€
188.00€

Shipping cost plus VAT not included , delivery in 7-14 business days

Description Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PMID:11847099, PMID:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PMID:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PMID:11847099). Plays a central role in controlling thyroid cell metabolism .
Other names Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R, TSHR, LGR3
Cellular localization Membrane, Multi-Pass Membrane, Basolateral Membrane, Multi-Pass Membrane,
Research area Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P16473
Product name Anti-TSHR Antibody
Catalog No IGX-40261
Supplier’s Catalog No IGX-40261
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IF
Recommended dilutions IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Thyrotropin receptor protein (21-413AA)
Specificity TSHR antibody detects endogenous level of TSHR protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).