Anti-Cbs / Cystathionine beta-synthase Antibody
Catalog No : IGX-40298
262.00€
188.00€
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| Description | Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine . Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons . | ||
|---|---|---|---|
| Other names | Cystathionine beta-synthase, EC 4.2.1.22, Beta-thionase, Serine sulfhydrase, Cbs | ||
| Cellular localization | Nucleus, Cytoplasm | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q91WT9 | ||
| Product name | Anti-Cbs / Cystathionine beta-synthase Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40298 | ||
| Supplier’s Catalog No | IGX-40298 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Mouse | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Mouse Cystathionine beta-synthase protein (2-561AA) | ||
| Specificity | Cbs antibody detects endogenous level of Cbs protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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