Anti-ATP6V0A2 / V-type proton ATPase isoform 2 Antibody
Catalog No : IGX-40328
262.00€
188.00€
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| Description | Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PMID:28296633). | ||
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| Other names | V-type proton ATPase 116 kDa subunit a isoform 2, V-ATPase 116 kDa isoform a2, Lysosomal H,+,-transporting ATPase V0 subunit a2, TJ6, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2, ATP6V0A2 | ||
| Cellular localization | Endosome Membrane, Membrane, Multi-Pass Membrane | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9Y487 | ||
| Product name | Anti-ATP6V0A2 / V-type proton ATPase isoform 2 Antibody | ||
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| Catalog No | IGX-40328 | ||
| Supplier’s Catalog No | IGX-40328 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human V-type proton ATPase 116 kDa subunit a isoform 2 protein (476-549AA) | ||
| Specificity | ATP6V0A2 antibody detects endogenous level of ATP6V0A2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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