Anti-FGF23 / Fibroblast growth factor 23 Antibody
Catalog No : IGX-40421
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL . Acts directly on the parathyroid to decrease PTH secretion . Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. | ||
|---|---|---|---|
| Other names | Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor, [Cleaved into: Fibroblast growth factor 23 N-terminal peptide, Fibroblast growth factor 23 C-terminal peptide], FGF23, HYPF | ||
| Cellular localization | Secreted | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9GZV9 | ||
| Product name | Anti-FGF23 / Fibroblast growth factor 23 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40421 | ||
| Supplier’s Catalog No | IGX-40421 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Fibroblast growth factor 23 protein (123-221AA) | ||
| Specificity | FGF23 antibody detects endogenous level of FGF23 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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