Anti-PDE1C Antibody
Catalog No : IGX-40432
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PMID:8557689, PMID:29860631). Has a high affinity for both cAMP and cGMP (PMID:8557689). Modulates the amplitude and duration of the cAMP signal in sensory cilia in response to odorant stimulation, hence contributing to the generation of action potentials. Regulates smooth muscle cell proliferation. Regulates the stability of growth factor receptors, including PDGFRB (Probable). | ||
|---|---|---|---|
| Other names | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, Cam-PDE 1C, EC 3.1.4.17, hCam-3, PDE1C | ||
| Cellular localization | Cytosol, Neuronal Cell Body | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q14123 | ||
| Product name | Anti-PDE1C Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40432 | ||
| Supplier’s Catalog No | IGX-40432 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C protein (542-634AA) | ||
| Specificity | PDE1C antibody detects endogenous level of PDE1C protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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