Anti-NHEJ1 Antibody

Catalog No : IGX-40444
262.00€
188.00€

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Description DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary (PMID:16439204, PMID:16439205, PMID:17470781). Binds DNA in a length-dependent manner (PMID:17317666).
Other names Non-homologous end-joining factor 1, Protein cernunnos, XRCC4-like factor, NHEJ1, XLF
Cellular localization Nucleus
Research area Epigenetics & Nuclear Signaling
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q9H9Q4
Product name Anti-NHEJ1 Antibody
Catalog No IGX-40444
Supplier’s Catalog No IGX-40444
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IF
Recommended dilutions IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Non-homologous end-joining factor 1 protein (225-296AA)
Specificity NHEJ1 antibody detects endogenous level of NHEJ1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).