Anti-CTNNA2 Antibody
Catalog No : IGX-40508
262.00€
188.00€
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| Description | May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system . Required for proper regulation of cortical neuronal migration and neurite growth (PMID:30013181). It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization (PMID:30013181). It thereby suppresses excessive actin branching which would impair neurite growth and stability (PMID:30013181). Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation . | ||
|---|---|---|---|
| Other names | Catenin alpha-2, Alpha N-catenin, Alpha-catenin-related protein, CTNNA2, CAPR | ||
| Cellular localization | Cytoskeleton, Nucleus, Membrane, Peripheral Membrane, , Cytoplasm, Adherens Junction, Axon | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P26232 | ||
| Product name | Anti-CTNNA2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40508 | ||
| Supplier’s Catalog No | IGX-40508 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Catenin alpha-2 protein (826-939AA) | ||
| Specificity | CTNNA2 antibody detects endogenous level of CTNNA2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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