Anti-CRYAA Antibody
Catalog No : IGX-40555
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Contributes to the transparency and refractive index of the lens (PMID:18302245). In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions (PMID:22120592, PMID:31792453). Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA (PMID:28935373). | ||
|---|---|---|---|
| Other names | Alpha-crystallin A chain, Heat shock protein beta-4, HspB4, [Cleaved into: Alpha-crystallin A,1-172, Alpha-crystallin A,1-168, Alpha-crystallin A,1-162,], CRYAA, CRYA1 HSPB4 | ||
| Cellular localization | Nucleus, Chromosome | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P02489 | ||
| Product name | Anti-CRYAA Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40555 | ||
| Supplier’s Catalog No | IGX-40555 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Alpha-crystallin A chain protein (98-173AA) | ||
| Specificity | CRYAA antibody detects endogenous level of CRYAA protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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