Anti-KIR2DS5 Antibody
Catalog No : IGX-40634
262.00€
188.00€
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| Description | Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity (PMID:28685972, PMID:18624290, PMID:18682925). Able to activate NK cells citotoxicity and cytokine production such as IFNG (PMID:18624290, PMID:24269691). Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 reprensented in this entry (PMID:28685972). | ||
|---|---|---|---|
| Other names | Killer cell immunoglobulin-like receptor 2DS5, CD158 antigen-like family member G, MHC class I NK cell receptor, Natural killer-associated transcript 9, NKAT-9, CD antigen CD158g, KIR2DS5, CD158G NKAT9 | ||
| Cellular localization | Membrane, Single-Pass Type I Membrane, Extracellular Side | ||
| Research area | Immunology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q14953 | ||
| Product name | Anti-KIR2DS5 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40634 | ||
| Supplier’s Catalog No | IGX-40634 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Killer cell immunoglobulin-like receptor 2DS5 protein (162-242AA) | ||
| Specificity | KIR2DS5 antibody detects endogenous level of KIR2DS5 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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