Anti-MPEG1 Antibody
Catalog No : IGX-40637
262.00€
188.00€
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| Description | Plays a key role in the innate immune response following bacterial infection by inserting into the bacterial surface to form pores . By breaching the surface of phagocytosed bacteria, allows antimicrobial effectors to enter the bacterial periplasmic space and degrade bacterial proteins such as superoxide dismutase sodC which contributes to bacterial virulence . Shows antibacterial activity against a wide spectrum of Gram-positive, Gram-negative and acid-fast bacteria (PMID:23753625, PMID:26402460, PMID:30609079). Reduces the viability of the intracytosolic pathogen L.monocytogenes by inhibiting acidification of the phagocytic vacuole of host cells which restricts bacterial translocation from the vacuole to the cytosol . Required for the antibacterial activity of reactive oxygen species and nitric oxide . | ||
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| Other names | Macrophage-expressed gene 1 protein, Macrophage gene 1 protein, Mpg-1, MPEG1 | ||
| Cellular localization | Cytoplasmic Vesicle Membrane, Single-Pass Type I Membrane, Secreted | ||
| Research area | Immunology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q2M385 | ||
| Product name | Anti-MPEG1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40637 | ||
| Supplier’s Catalog No | IGX-40637 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Macrophage-expressed gene 1 protein (537-633AA) | ||
| Specificity | MPEG1 antibody detects endogenous level of MPEG1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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