Anti-CHRM2 / Cholinergic receptor muscarinic 2 Antibody
Catalog No : IGX-40689
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol. | ||
|---|---|---|---|
| Other names | Muscarinic acetylcholine receptor M2, CHRM2 | ||
| Cellular localization | Membrane, Multi-Pass Membrane, Postsynaptic Membrane, Multi-Pass Membrane | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P08172 | ||
| Product name | Anti-CHRM2 / Cholinergic receptor muscarinic 2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40689 | ||
| Supplier’s Catalog No | IGX-40689 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Peptide sequence from Human Muscarinic acetylcholine receptor M2 protein (3-20AA) | ||
| Specificity | CHRM2 antibody detects endogenous level of CHRM2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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