Anti-CACNA1D / CaV1.3 Antibody

Catalog No : IGX-40716
262.00€
188.00€

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Description Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines.
Other names Voltage-dependent L-type calcium channel subunit alpha-1D, Calcium channel, L type, alpha-1 polypeptide, isoform 2, Voltage-gated calcium channel subunit alpha Cav1.3, CACNA1D, CACH3 CACN4 CACNL1A2 CCHL1A2
Cellular localization Membrane, Multi-Pass Membrane
Research area Neuroscience
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q01668
Product name Anti-CACNA1D / CaV1.3 Antibody
Catalog No IGX-40716
Supplier’s Catalog No IGX-40716
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IF
Recommended dilutions IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Voltage-dependent L-type calcium channel subunit alpha-1D protein (1691-1806AA)
Specificity CACNA1D antibody detects endogenous level of CACNA1D protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).