Anti-C5 / Complement C5a anaphylatoxin Antibody

Catalog No : IGX-40801
262.00€
188.00€

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Description Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
Other names Complement C5a anaphylatoxin, C5
Cellular localization Secreted
Research area Immunology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P01032
Product name Anti-C5 / Complement C5a anaphylatoxin Antibody
Catalog No IGX-40801
Supplier’s Catalog No IGX-40801
Supplier ImuGeX
Host species Rabbit
Species reactivity Pig
Applications ELISA, IHC
Recommended dilutions IHC: 1:10-1:100
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Pig Complement C5a anaphylatoxin protein (1-74AA)
Specificity C5 antibody detects endogenous level of C5 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).