Anti-C5 / Complement C5a anaphylatoxin Antibody
Catalog No : IGX-40801
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
Description | Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation. | ||
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Other names | Complement C5a anaphylatoxin, C5 | ||
Cellular localization | Secreted | ||
Research area | Immunology | ||
Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
Uniprot ID | P01032 |
Product name | Anti-C5 / Complement C5a anaphylatoxin Antibody | ||
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Catalog No | IGX-40801 | ||
Supplier’s Catalog No | IGX-40801 | ||
Supplier | ImuGeX | ||
Host species | Rabbit | ||
Species reactivity | Pig | ||
Applications | ELISA, IHC | ||
Recommended dilutions | IHC: 1:10-1:100 | ||
Molecular weight | N/A | ||
Conjugate | Unconjugated | ||
Immunogen | Recombinant Pig Complement C5a anaphylatoxin protein (1-74AA) | ||
Specificity | C5 antibody detects endogenous level of C5 protein |
Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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Clonality | Polyclonal | ||
Isotype | IgG | ||
Clone ID | N/A | ||
Concentration | 1 mg/mL | ||
Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
Formulation | Liquid | ||
Purification | This antibody is immunogen affinity purified. | ||
Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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