Anti-ROR1 Antibody
Catalog No : IGX-40806
262.00€
188.00€
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| Description | Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PMID:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PMID:25029443, PMID:27162350). In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells (PMID:27162350). | ||
|---|---|---|---|
| Other names | Inactive tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1, ROR1, NTRKR1 | ||
| Cellular localization | Membrane, Single-Pass Type I Membrane, Axon | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q01973 | ||
| Product name | Anti-ROR1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40806 | ||
| Supplier’s Catalog No | IGX-40806 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:10-1:100 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Inactive tyrosine-protein kinase transmembrane receptor ROR1 protein (30-391AA) | ||
| Specificity | ROR1 antibody detects endogenous level of ROR1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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