Anti-NFATC1 Antibody

Catalog No : IGX-40905
262.00€
188.00€

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Description Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PMID:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function .
Other names Nuclear factor of activated T-cells, cytoplasmic 1, NF-ATc1, NFATc1, NFAT transcription complex cytosolic component, NF-ATc, NFATc, NFATC1, NFAT2 NFATC
Cellular localization Nucleus, Cytoplasm
Research area Immunology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID O95644
Product name Anti-NFATC1 Antibody
Catalog No IGX-40905
Supplier’s Catalog No IGX-40905
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:1000-1:2000, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Nuclear factor of activated T-cells, cytoplasmic 1 protein (48-406AA)
Specificity NFATC1 antibody detects endogenous level of NFATC1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).