Anti-MRPL41 Antibody
Catalog No : IGX-41512
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Component of the mitochondrial ribosome large subunit (PMID:28892042, PMID:25838379, PMID:25278503). Also involved in apoptosis and cell cycle (PMID:16024796, PMID:16256947). Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (PMID:16024796). | ||
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| Other names | 39S ribosomal protein L41, mitochondrial, L41mt, MRP-L41, 39S ribosomal protein L27 homolog, Bcl-2-interacting mitochondrial ribosomal protein L41, Cell proliferation-inducing gene 3 protein, MRP-L27 homolog, Mitochondrial large ribosomal subunit protein mL41, MRPL41, BMRP MRPL27 RPML27 | ||
| Cellular localization | Mitochondrion | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q8IXM3 | ||
| Product name | Anti-MRPL41 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41512 | ||
| Supplier’s Catalog No | IGX-41512 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human 39S ribosomal protein L41, mitochondrial protein (14-137AA) | ||
| Specificity | MRPL41 antibody detects endogenous level of MRPL41 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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