Anti-DENND1A Antibody
Catalog No : IGX-41560
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes (PMID:20154091, PMID:20937701). Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns3P . | ||
|---|---|---|---|
| Other names | DENN domain-containing protein 1A, Connecdenn 1, Connecdenn, Protein FAM31A, DENND1A, FAM31A KIAA1608 | ||
| Cellular localization | Presynaptic Membrane, Clathrin-Coated Vesicle Membrane, Peripheral Membrane | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q8TEH3 | ||
| Product name | Anti-DENND1A Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41560 | ||
| Supplier’s Catalog No | IGX-41560 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human DENN domain-containing protein 1A protein (1-559AA) | ||
| Specificity | DENND1A antibody detects endogenous level of DENND1A protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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