Anti-RDH12 Antibody
Catalog No : IGX-41617
262.00€
188.00€
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| Description | Retinoids dehydrogenase/reductase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinal. Shows very weak activity towards 13-cis-retinol (PMID:15865448, PMID:12226107). Also exhibits activity, albeit with lower affinity than for retinaldehydes, towards lipid peroxidation products (C9 aldehydes) such as 4-hydroxynonenal and trans-2-nonenal (PMID:19686838, PMID:15865448). May play an important function in photoreceptor cells to detoxify 4-hydroxynonenal and potentially other toxic aldehyde products resulting from lipid peroxidation (PMID:19686838). Has no dehydrogenase activity towards steroids (PMID:15865448, PMID:12226107). | ||
|---|---|---|---|
| Other names | Retinol dehydrogenase 12, EC 1.1.1.-, All-trans and 9-cis retinol dehydrogenase, Short chain dehydrogenase/reductase family 7C member 2, RDH12, SDR7C2 | ||
| Cellular localization | Endoplasmic Reticulum Membrane | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q96NR8 | ||
| Product name | Anti-RDH12 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41617 | ||
| Supplier’s Catalog No | IGX-41617 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Retinol dehydrogenase 12 protein (1-316AA) | ||
| Specificity | RDH12 antibody detects endogenous level of RDH12 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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