Anti-DPH1 Antibody
Catalog No : IGX-41772
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers . Plays a role in embryonic growth, organogenesis and postnatal survival . | ||
|---|---|---|---|
| Other names | 2-,3-amino-3-carboxypropyl,histidine synthase subunit 1, EC 2.5.1.108, Diphthamide biosynthesis protein 1, Diphtheria toxin resistance protein 1, Ovarian cancer-associated gene 1 protein, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1, DPH1, DPH2L DPH2L1 OVCA1 | ||
| Cellular localization | Cytoplasm, Nucleus | ||
| Research area | Cancer | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9BZG8 | ||
| Product name | Anti-DPH1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41772 | ||
| Supplier’s Catalog No | IGX-41772 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 protein (192-318AA) | ||
| Specificity | DPH1 antibody detects endogenous level of DPH1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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