Anti-ACSL5 Antibody
Catalog No : IGX-41860
262.00€
188.00€
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| Description | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PMID:17681178, PMID:24269233, PMID:22633490). ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage . Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids . It was suggested that it may also stimulate fatty acid oxidation . At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells. | ||
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| Other names | Long-chain-fatty-acid--CoA ligase 5, EC 6.2.1.3, Long-chain acyl-CoA synthetase 5, LACS 5, ACSL5, ACS5 FACL5 | ||
| Cellular localization | Membrane, Endoplasmic Reticulum, Endoplasmic Reticulum Membrane, Single-Pass Type Iii Membrane, Mitochondrion, Mitochondrion Outer Membrane | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9ULC5 | ||
| Product name | Anti-ACSL5 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41860 | ||
| Supplier’s Catalog No | IGX-41860 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Long-chain-fatty-acid--CoA ligase 5 protein (33-683AA) | ||
| Specificity | ACSL5 antibody detects endogenous level of ACSL5 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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