Anti-ERBB3 Antibody
Catalog No : IGX-41915
237.00€
175.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PMID:20682778). May also be activated by CSPG5 (PMID:15358134). Involved in the regulation of myeloid cell differentiation (PMID:27416908). | ||
|---|---|---|---|
| Other names | Receptor tyrosine-protein kinase erbB-3, EC 2.7.10.1, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, ERBB3, HER3 | ||
| Cellular localization | Membrane, Single-Pass Type I Membrane, Secreted | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P21860 | ||
| Product name | Anti-ERBB3 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41915 | ||
| Supplier’s Catalog No | IGX-41915 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Receptor tyrosine-protein kinase erbB-3 protein (20-285AA) | ||
| Specificity | ERBB3 antibody detects endogenous level of ERBB3 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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