Anti-KIF2C Antibody

Catalog No : IGX-41973
237.00€
175.00€

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Description In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PMID:21820309). Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (PMID:19060894). Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (PMID:23891108).
Other names Kinesin-like protein KIF2C, Kinesin-like protein 6, Mitotic centromere-associated kinesin, MCAK, KIF2C, KNSL6
Cellular localization Centromere, Cytoskeleton, Kinetochore, Nucleus
Research area Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q99661
Product name Anti-KIF2C Antibody
Catalog No IGX-41973
Supplier’s Catalog No IGX-41973
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Kinesin-like protein KIF2C protein (1-190AA)
Specificity KIF2C antibody detects endogenous level of KIF2C protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).