Anti-LZTR1 Antibody
Catalog No : IGX-42705
237.00€
175.00€
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| Description | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS) (PMID:30442762, PMID:30442766, PMID:30481304). Is a negative regulator of RAS-MAPK signaling that acts by controlling Ras levels and decreasing Ras association with membranes (PMID:30442762, PMID:30442766, PMID:30481304). | ||
|---|---|---|---|
| Other names | Leucine-zipper-like transcriptional regulator 1, LZTR-1, LZTR1, TCFL2 | ||
| Cellular localization | Golgi Apparatus, Recycling Endosome, Endomembrane System | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q8N653 | ||
| Product name | Anti-LZTR1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42705 | ||
| Supplier’s Catalog No | IGX-42705 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Leucine-zipper-like transcriptional regulator 1 protein (300-545AA) | ||
| Specificity | LZTR1 antibody detects endogenous level of LZTR1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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