Anti-NUAK2 Antibody
Catalog No : IGX-42819
237.00€
175.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1. | ||
|---|---|---|---|
| Other names | NUAK family SNF1-like kinase 2, EC 2.7.11.1, Omphalocele kinase 2, SNF1/AMP kinase-related kinase, SNARK, NUAK2, OMPHK2 SNARK | ||
| Cellular localization | Nucleus, Cytoplasm | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9H093 | ||
| Product name | Anti-NUAK2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42819 | ||
| Supplier’s Catalog No | IGX-42819 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human NUAK family SNF1-like kinase 2 protein (479-628AA) | ||
| Specificity | NUAK2 antibody detects endogenous level of NUAK2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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