Anti-HAND1 Antibody

Catalog No : IGX-42935
237.00€
175.00€

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Description Transcription factor that plays an essential role in both trophoblast giant cell differentiation and in cardiac morphogenesis . Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) . Acts as a transcriptional repressor of SOX15 . In the adult, could be required for ongoing expression of cardiac-specific genes (PMID:9931445).
Other names Heart- and neural crest derivatives-expressed protein 1, Class A basic helix-loop-helix protein 27, bHLHa27, Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1, eHAND, HAND1, BHLHA27 EHAND
Cellular localization Nucleoplasm, Nucleolus
Research area Epigenetics & Nuclear Signaling
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID O96004
Product name Anti-HAND1 Antibody
Catalog No IGX-42935
Supplier’s Catalog No IGX-42935
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Heart- and neural crest derivatives-expressed protein 1 protein (16-215AA)
Specificity HAND1 antibody detects endogenous level of HAND1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).