Anti-DSTYK Antibody
Catalog No : IGX-42957
237.00€
175.00€
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| Description | Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation (PMID:23862974, PMID:28157540). Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death (PMID:15178406). In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types (PMID:28157540). | ||
|---|---|---|---|
| Other names | Dual serine/threonine and tyrosine protein kinase, EC 2.7.12.1, Dusty protein kinase, Dusty PK, RIP-homologous kinase, Receptor-interacting serine/threonine-protein kinase 5, Sugen kinase 496, SgK496, DSTYK, KIAA0472 RIP5 RIPK5 SGK496 | ||
| Cellular localization | Membrane, Apical Membrane, Basolateral Membrane, Cytoplasm, Cell Junction | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q6XUX3 | ||
| Product name | Anti-DSTYK Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42957 | ||
| Supplier’s Catalog No | IGX-42957 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Dual serine/threonine and tyrosine protein kinase protein (680-929AA) | ||
| Specificity | DSTYK antibody detects endogenous level of DSTYK protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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