Anti-SAE1 Antibody

Catalog No : IGX-42959
237.00€
175.00€

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Description The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Other names SUMO-activating enzyme subunit 1, Ubiquitin-like 1-activating enzyme E1A, [Cleaved into: SUMO-activating enzyme subunit 1, N-terminally processed], SAE1, AOS1 SUA1 UBLE1A
Cellular localization Nucleus
Research area Cell Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q9UBE0
Product name Anti-SAE1 Antibody
Catalog No IGX-42959
Supplier’s Catalog No IGX-42959
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human SUMO-activating enzyme subunit 1 protein (1-346AA)
Specificity SAE1 antibody detects endogenous level of SAE1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).