Anti-DUOX1 Antibody

Catalog No : IGX-43081
237.00€
175.00€

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Description Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Other names Dual oxidase 1, EC 1.11.1.-, EC 1.6.3.1, Large NOX 1, Long NOX 1, NADPH thyroid oxidase 1, Thyroid oxidase 1, DUOX1, DUOX LNOX1 THOX1
Cellular localization Apical Membrane, Multi-Pass Membrane
Research area Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q9NRD9
Product name Anti-DUOX1 Antibody
Catalog No IGX-43081
Supplier’s Catalog No IGX-43081
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Dual oxidase 1 protein (1312-1551AA)
Specificity DUOX1 antibody detects endogenous level of DUOX1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).