Anti-WNT1 Antibody
Catalog No : IGX-43248
262.00€
188.00€
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| Description | Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (PMID:23499309, PMID:26902720, PMID:28528193, PMID:23656646). In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling . Plays an essential role in the development of the embryonic brain and central nervous system (CNS) . Has a role in osteoblast function, bone development and bone homeostasis (PMID:23499309, PMID:23656646). | ||
|---|---|---|---|
| Other names | Proto-oncogene Wnt-1, Proto-oncogene Int-1 homolog, WNT1, INT1 | ||
| Cellular localization | Extracellular Matrix, Secreted | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P04628 | ||
| Product name | Anti-WNT1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43248 | ||
| Supplier’s Catalog No | IGX-43248 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Proto-oncogene Wnt-1 protein (142-288AA) | ||
| Specificity | WNT1 antibody detects endogenous level of WNT1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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