Anti-UFM1 Antibody
Catalog No : IGX-43286
262.00€
188.00€
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| Description | Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer (PMID:15071506, PMID:20018847, PMID:29868776). The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PMID:15071506, PMID:20018847, PMID:29868776). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes (PMID:15071506, PMID:20018847). TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PMID:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable). | ||
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| Other names | Ubiquitin-fold modifier 1, UFM1, C13orf20 | ||
| Cellular localization | Cytoplasm, Nucleus | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P61960 | ||
| Product name | Anti-UFM1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43286 | ||
| Supplier’s Catalog No | IGX-43286 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Ubiquitin-fold modifier 1 protein (11-63AA) | ||
| Specificity | UFM1 antibody detects endogenous level of UFM1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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