Anti-CEP19 / Centrosomal protein of 19 kDa Antibody
Catalog No : IGX-43337
262.00€
188.00€
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| Description | Required for ciliation (PMID:28625565, PMID:28428259, PMID:28659385). Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia (PMID:28625565, PMID:28428259). Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring to the centrosomes (PMID:28659385). | ||
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| Other names | Centrosomal protein of 19 kDa, Cep19, CEP19, C3orf34 | ||
| Cellular localization | Cytoskeleton, Centriole, Spindle Pole, Cilium Basal Body | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q96LK0 | ||
| Product name | Anti-CEP19 / Centrosomal protein of 19 kDa Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43337 | ||
| Supplier’s Catalog No | IGX-43337 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Centrosomal protein of 19 kDa protein (1-163AA) | ||
| Specificity | CEP19 antibody detects endogenous level of CEP19 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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