Anti-CMTR2 Antibody

Catalog No : IGX-43936
262.00€
188.00€

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Description S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m7GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m7GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N7 methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.
Other names Cap-specific mRNA, nucleoside-2'-O-,-methyltransferase 2, EC 2.1.1.296, Cap methyltransferase 2, Cap2 2'O-ribose methyltransferase 2, HMTr2, MTr2, FtsJ methyltransferase domain-containing protein 1, Protein adrift homolog, CMTR2, AFT FTSJD1
Cellular localization Cytoplasm, Nucleus
Research area Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q8IYT2
Product name Anti-CMTR2 Antibody
Catalog No IGX-43936
Supplier’s Catalog No IGX-43936
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:20-1:200, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 protein (301-600AA)
Specificity CMTR2 antibody detects endogenous level of CMTR2 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).