Anti-IZUMO1 Antibody

Catalog No : IGX-43937
262.00€
188.00€

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Description Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg (PMID:15759005). The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion (PMID:15759005). The ligand-receptor interaction probably does not act as a membrane 'fusogen' (PMID:15759005).
Other names Izumo sperm-egg fusion protein 1, Oocyte binding/fusion factor, OBF, Sperm-specific protein izumo, IZUMO1
Cellular localization Membrane, Single-Pass Type I Membrane, Acrosome Membrane
Research area Developmental Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q8IYV9
Product name Anti-IZUMO1 Antibody
Catalog No IGX-43937
Supplier’s Catalog No IGX-43937
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:20-1:200, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Izumo sperm-egg fusion protein 1 protein (22-292AA)
Specificity IZUMO1 antibody detects endogenous level of IZUMO1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).