Anti-SNX14 Antibody
Catalog No : IGX-44210
262.00€
188.00€
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| Description | Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking . Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes (Probable). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes (PMID:25848753). Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)) (PMID:25848753, PMID:25148684). | ||
|---|---|---|---|
| Other names | Sorting nexin-14, SNX14 | ||
| Cellular localization | Late Endosome Membrane, Multi-Pass Membrane, Lysosome Membrane, Dendrite | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9Y5W7 | ||
| Product name | Anti-SNX14 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44210 | ||
| Supplier’s Catalog No | IGX-44210 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Sorting nexin-14 protein (601-893AA) | ||
| Specificity | SNX14 antibody detects endogenous level of SNX14 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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