Anti-CWC22 Antibody
Catalog No : IGX-44243
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Required for pre-mRNA splicing as component of the spliceosome (PMID:12226669, PMID:11991638, PMID:22961380, PMID:28502770, PMID:28076346, PMID:29360106, PMID:29301961). Promotes exon-junction complex (EJC) assembly (PMID:22959432, PMID:22961380). Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. | ||
|---|---|---|---|
| Other names | Pre-mRNA-splicing factor CWC22 homolog, Nucampholin homolog, fSAPb, CWC22, KIAA1604 NCM | ||
| Cellular localization | Nucleus, Nucleus Speckle | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9HCG8 | ||
| Product name | Anti-CWC22 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44243 | ||
| Supplier’s Catalog No | IGX-44243 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Pre-mRNA-splicing factor CWC22 homolog protein (360-623AA) | ||
| Specificity | CWC22 antibody detects endogenous level of CWC22 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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